|Related Categories||Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antiparasitic / Antiprotozoal / Anthelminthic, Biochemicals and Reagents,|
Suitable for inhibition of various mammalian alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor).
Intestinal alkaline phosphatases are only slightly inhibited.
Not for veterinary use.
Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors.1 Very effective in treatment of ascariasis (hookworm infestation).2 Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages.3
5, 10 g in poly bottle
Levamisole hydrochloride is soluble in water at 50mg/mL yielding a clear, colorless solution. Solutions are stable at 2-8°C for ~1 month.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P301 + P310|
|Personal Protective Equipment||Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||25|
|Safety Statements (Europe)||36/37/39-45|
|RIDADR||UN 2811 6.1 / PGIII|
Histamine is a biogenic amine that stimulates multiple histamine receptor types. In mammals, histamine is found within granules of basophils and mast cells (>90% of body stores) and within tuberomamm...
Keywords: Atomic layer deposition, Cardiovascular, Ligands, Metabolism, Methylations, Microwave synthesis, Oxidations
Development and evaluation of age-appropriate film-coated tablets of levamisole for paediatric use (2 - 18 years). Kreeftmeijer-Vegter AR, de Meijer M, Wegman KA, et al. Expert Opin. Drug Deliv. 10(3), 293-300, (2013)
Matrix gla protein and alkaline phosphatase are differently modulated in human dermal fibroblasts from PXE patients and controls. Boraldi F, Annovi G, Vermeer C, et al. J. Invest. Dermatol. 133(4), 946-54, (2013)
Levamisole-induced leukocytoclastic vasculitis and neutropenia in a patient with cocaine use: an extensive case with necrosis of skin, soft tissue, and cartilage. Arora NP, Jain T, Bhanot R, et al. Addict. Sci. Clin. Pract. 7(1), 19, (2012)
Prevalence of gastrointestinal helminths and anthelmintic resistance on small-scale farms in Gauteng Province, South Africa. Tsotetsi AM, Njiro S, Katsande TC, et al. Trop. Anim. Health Prod. 45(3), 751-61, (2013)
In vitro anthelmintic activity of aqueous leaf extract of Annona muricata L. (Annonaceae) against Haemonchus contortus from sheep. Ferreira LE, Castro PM, Chagas AC, et al. Exp. Parasitol. 134(3), 327-32, (2013)
Superior efficacy of azithromycin and levamisole vs. azithromycin in the treatment of inflammatory acne vulgaris: an investigator blind randomized clinical trial on 169 patients. Rassai S, Mehri M, Yaghoobi R, et al. Int. J. Clin. Pharmacol. Ther. 51(6), 490-4, (2013)
TNAP and EHD1 are over-expressed in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties. Deracinois B, Duban-Deweer S, Pottiez G, et al. PLoS ONE 7(10), e48428, (2012)
Effects of levamisole and ranitidine on antibody-forming responses induced by killed Mycoplasma vaccine antigens in Saanen goats. Temizel EM, Onat K, Mecitoglu Z, et al. Vet. Rec. 171(23), 597, (2012)
Pharmacological assays reveal age-related changes in synaptic transmission at the Caenorhabditis elegans neuromuscular junction that are modified by reduced insulin signalling. Mulcahy B, Holden-Dye L, and O'Connor V J. Exp. Biol. 216(Pt 3), 492-501, (2013)
Phenotypic Characterization of Two Ancylostoma caninum Isolates with Different Susceptibilities to the Anthelmintic Pyrantel Steven R. Kopp, Glen T. Coleman, et al. Antimicrob. Agents Chemother. 52, 3980-3986, (2008)
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