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L9756 Sigma

(−)-Tetramisole hydrochloride

≥99% (GC)

Synonym: (S)-(−)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride, L(−)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride, Levamisole hydrochloride

  • CAS Number 16595-80-5

  • Empirical Formula (Hill Notation) C11H12N2S · HCl

  • Molecular Weight 240.75

  •  Beilstein Registry Number 4358988

  •  EC Number 240-654-6

  •  MDL number MFCD00012675

  •  PubChem Substance ID 24278526

  • Popular Documents:  FTNMR (PDF)  

Description

Application

Suitable for inhibition of various mammalian alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor).
Intestinal alkaline phosphatases are only slightly inhibited.
Not for veterinary use.

Biochem/physiol Actions

Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors.1 Very effective in treatment of ascariasis (hookworm infestation).2 Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages.3

Packaging

5, 10 g in poly bottle

Other Notes

Levamisole hydrochloride is soluble in water at 50mg/mL yielding a clear, colorless solution. Solutions are stable at 2-8°C for ~1 month.

Price and Availability


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