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M0567 Sigma

Microsomes from Liver, Pooled

from human male

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Drug and Xenobiotic Metabolism, Liver Preparations and Fractions, Multi-Drug Resistance and Drug Metabolism,
biological source   from human male
assay   ~10 mg per vial
shipped in   dry ice
storage temp.   −70°C

Description

Application

Microsomes from liver have been used in a study to assess differences in enzymatic activities between normal rat livers and from liver after partial hepatectomy. They have also been used in a study to investigate the carbon monoxide-binding pigment in liver microsomes.

Biochem/physiol Actions

Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.

N-glucuronidation of various 1-substituted imidazoles was found to occur in human liver microsomes.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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