• USA Home
  • M0807 - Anti-Matrix Metalloproteinase-12, C-Terminal antibody produced in rabbit

EMAIL THIS PAGE TO A FRIEND
M0807 Sigma

Anti-Matrix Metalloproteinase-12, C-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-MMP-12

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix, Antibodies to Matrix Metalloproteinases and TIMPs,
species reactivity   human
application(s)   immunohistochemistry (frozen sections): suitable
  immunoprecipitation: suitable
  indirect ELISA: suitable
  western blot: 1:1,000
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MMP12(4321)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the C-terminal of human matrix metalloproteinase-12 (macrophage elastase).

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Specificity

Reacts with reduced MMP-12. The C-terminal recognizes most active forms of MMP-12. The hemopexin domain is cleaved in the final form of MMP-12 and the antibody does not detect this final form. The zymogen is approximately 54 kDa and is quickly activated to the 45 kDa form which breaks down to a cascade of active forms, ending with a 22 kDa form.

Price and Availability


Detect Your Unseen Protein

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?