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  • M0939 - Anti-α-MSH antibody produced in rabbit

M0939 Sigma

Anti-α-MSH antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-α-Melanocyte Stimulating Hormone



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Hormones, Antibodies to Pituitary Hormones,
species reactivity   human
application(s)   microarray: suitable
  radioimmunoassay: 1:3,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 1664.9 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... POMC(5443)
biological source   rabbit
conjugate   unconjugated



synthetic α-MSH peptide conjugated to bovine serum albumin.

General description

Cross-reacts with des-Ac-α-MSH and [Val-OH13] α-MSH. Minimal cross-reactivity is observed with human ACTH (1-39) and ACTH (1-24).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Anti-α-MSH antibody produced in rabbit was used for immunohistochemistry of formalin-fixed, paraffin-embedded tissue sections of basal cell carcinoma.

Biochem/physiol Actions

α-Melanocyte Stimulating Hormone (α-MSH) stimulates the production of melanin in melanocytes and induced pigmentation and skin darkening. It increases the activity of tyrosinase that induces melanogenesis. α-MSH has potent anti-inflammatory effects and is also a neuromodulator. Analogs of α-MSH may be used to study melanogenesis and neuromodulation.

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