• USA Home

  • M107 - (+)-MK-801 hydrogen maleate

EMAIL THIS PAGE TO A FRIEND

M107 Sigma

(+)-MK-801 hydrogen maleate

powder

DOWNLOAD MSDS (PDF)

Synonym: (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate, Dizocilpine hydrogen maleate

  • CAS Number 77086-22-7

  • Empirical Formula (Hill Notation) C16H15N · C4H4O4

  • Molecular Weight 337.37

  •  EC Number 278-614-5

  •  MDL number MFCD00082465

  •  PubChem Substance ID 24277988

(+)-MK-801 hydrogen maleate powder
icon image

Properties

Related Categories Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels,
form   powder
optical activity   [α]25/D +117°, c = 1 in methanol(lit.)
color   white
solubility   DMSO: >20 mg/mL
  H2O: soluble6 mg/mL
  0.1 M HCl: soluble
  ethanol: soluble
Gene Information   human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)
Show More (9)

Description

Biochem/physiol Actions

Highly potent and selective non-competitive NMDA glutamate receptor antagonist that acts at the NMDA receptor-operated ion channel as an open channel blocker. Inhibits behavioral sensitization to psychostimulants and ethanol.

Price and Availability

Customers Also Viewed

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?