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M108 Sigma

(−)-MK-801 hydrogen maleate

≥98% (HPLC)

Synonym: (5R,10S)-(–)-5-Methyl-10,11-dihydro-5H-dibenzo­[a,d]­cyclo­hepten-5,10-imine hydrogen maleate

  • CAS Number 77086-19-2

  • Empirical Formula (Hill Notation) C16H15N · C4H4O4

  • Molecular Weight 337.37

  •  MDL number MFCD00082466

  •  PubChem Substance ID 24277961

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators,
InChI Key   QLTXKCWMEZIHBJ-FWHYOZOBSA-N
assay   ≥98% (HPLC)
form   solid
optical activity   [α]25/D −117.7°, c = 1 in methanol(lit.)
color   white
solubility   DMSO: >20 mg/mL
storage temp.   room temp
Gene Information   human ... GRIN1(2902), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... GRIN1(14810), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... GRIN1(24408), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

Description

Biochem/physiol Actions

Less active enantiomer of (+)-MK-801 hydrogen maleate

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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