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M1314 Sigma

Mer/Fc Chimera human

>90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

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Properties

Related Categories Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Oncoproteins,
recombinant   expressed in baculovirus infected Sf21 cells
assay   >90% (SDS-PAGE)
form   lyophilized powder
mol wt   calculated mol wt 78.9 kDa
  mol wt 100-110 kDa by SDS-PAGE (reducing)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... MERTK(10461)

Description

Analysis Note

Measured by its ability to bind recombinant human Gas6.

Biochem/physiol Actions

This receptor binds the vitamin K-dependent protein growth-arrest-specific gene 6 (Gas6) which induces receptor autophosphorylation and downstream signaling pathways leading to cell proliferation, migration, or the prevention of apoptosis.

General description

Extracellular domain of human Mer (amino acids 1-499) fused to the C-terminal Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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