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M2028 Sigma

Capsaicin

≥95%, from Capsicum sp.

Synonym: 8-Methyl-N-vanillyl-trans-6-nonenamide

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Properties

Related Categories Alkaloid, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology,
biological source   from Capsicum sp.
InChI Key   YKPUWZUDDOIDPM-SOFGYWHQSA-N
assay   ≥95%
mp   62-65 °C(lit.)
solubility   H2O: insoluble
  ethanol: soluble
storage temp.   2-8°C
Gene Information   human ... CYP1A2(1544), TRPV1(7442)
rat ... Trpv1(83810), Trpv4(66026)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

1 g in glass bottle

250 mg in glass bottle

50 mg in poly bottle

Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
RA8530000
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C
Protocols & Articles

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Peer-Reviewed Papers
15

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