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M218 Sigma

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α4 Subunit) antibody produced in rat

~1 mg/mL, clone mAb 299, purified immunoglobulin, buffered aqueous solution

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neurotransmission, Antibodies to Ion Channels,
species reactivity   rat, chicken, human
application(s)   immunohistochemistry (frozen sections): 1:800
  radioimmunoassay: suitable
clone   mAb 299, monoclonal
concentration   ~1 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CHRNA4(1137)
rat ... Chrna4(25590)
biological source   rat
conjugate   unconjugated

Description

Immunogen

nicotinic acetylcholine receptor (AchR) from the rat brain.

Physical form

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

Specificity

Binds to native and denatured α4 AchR. May be used to quantitate α4 AchR′s on the cell surface. The epitope is located on the extracellular surface of the α4 subunit of the AchR.

Legal Information

Sold with permission of the Salk Institute

Packaging

100 μL in glass insert

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Safety Information

Personal Protective Equipment  Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
RIDADR  NONH for all modes of transport
WGK Germany  2
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Peer-Reviewed Papers
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