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M221 Sigma

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α3 Subunit) antibody produced in rat

~5 mg/mL, clone mAb 313, affinity isolated antibody, buffered aqueous solution

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neurotransmission, Antibodies to Ion Channels,
species reactivity   chicken
application(s)   immunohistochemistry (frozen sections): 1:4,000
clone   mAb 313, monoclonal
concentration   ~5 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
isotype   IgG2a
shipped in   dry ice
storage temp.   −20°C
Gene Information   chicken ... CHRNA3(386578)
biological source   rat
conjugate   unconjugated

Description

Immunogen

recombinant large cytoplasmic domain of the α3 subunit (amino acids 315-441) of the nicotinic acetylcholine receptor from chick.

Physical form

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

Specificity

Binds to native and denatured detergent-solubilized α3 subunit of AchR. Does not bind α1, α4, α5, α7, α8 and β2.

Legal Information

Sold with permission of the Salk Institute

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