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M2912 Sigma

Microcystin LR from Microcystis aeruginosa

≥95% (HPLC), solid film

Synonym: 5-L-Arginine-microcystin LA


Biochem/physiol Actions

Potent inhibitor of protein phosphatase Types 1 and 2A; has no effect on protein kinase. Hepatic tumor promoter in experimental animal model.1

Other Notes

Hepatotoxic cyclic heptapeptide.


Stock solutions can be diluted in 50 mM Tris-HCl, pH 7.0, containing 0.03% Brij 35; phosphatase inhibition will be retained for up to 1 month when stored at concentrations up to 0.01 nM.

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

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