|Related Categories||Application Index, Bacteria, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes,|
|solubility||ethanol: soluble1 mg/mL|
Potent inhibitor of protein phosphatase Types 1 and 2A; has no effect on protein kinase. Hepatic tumor promoter in experimental animal model.1
Hepatotoxic cyclic heptapeptide.
Stock solutions can be diluted in 50 mM Tris-HCl, pH 7.0, containing 0.03% Brij 35; phosphatase inhibition will be retained for up to 1 month when stored at concentrations up to 0.01 nM.
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≥90% (HPLC), solid
5 μg/mL in methanol (each), analytical standard, for environmental analysis
10 μg/mL in methanol, analytical standard, for environmental analysis
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P264-P280-P301 + P310-P302 + P350-P305 + P351 + P338|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T+|
|Risk Statements (Europe)||26/27/28-36/37/38-43|
|Safety Statements (Europe)||26-36/37/39-45|
|RIDADR||UN 2811 6.1/PG 1|
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation
1. Chronic Microcystin Exposure Induces Hepatocyte Proliferation with Increased Expression of Mitotic and Cyclin-associated Genes in P53-deficient Mice. Clark, S. P., et al. Toxicol. Pathol., (2008)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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