M2939 Sigma

Methyl arachidonyl fluorophosphonate

≥98%, methyl acetate solution (10 mg/mL)

DOWNLOAD MSDS (PDF)

Synonym: MAPF, Phosphonofluoridic acid, methyl-5Z,8Z,11Z,14Z-eicosatetraenyl ester

  • Empirical Formula (Hill Notation) C21H36FO2P

  • Molecular Weight 370.48

  •  EC Number 201-185-2

  •  MDL number MFCD03095722

Description

Biochem/physiol Actions

MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A2, but not secretory phospholipase A2. MAFP is also a potent acetylcholinesterase inhibitor.

Preparation Note

To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice.

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