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  • M3550 - Anti-MAP Kinase Activated Protein Kinase-2 (MAPKAPK-2) antibody produced in rabbit

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M3550 Sigma

Anti-MAP Kinase Activated Protein Kinase-2 (MAPKAPK-2) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, M1-MAR,
species reactivity   mouse, bovine, human
application(s)   microarray: suitable
  western blot: 1:2,000 using MDBK whole cell extract
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 45 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MAPKAPK2(9261)
mouse ... Mapkapk2(17164)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

A synthetic peptide corresponding to amino acids 343-358 of human MAP kinase activated protein kinase 2 (MAPKAPK-2), coupled to KLH. The sequence is identical in mouse MAPKAPK-2.

General description

MAP Kinase Activated Protein Kinase-2 (MAPKAPK-2) is a protein that belongs to Ser/Thr protein kinase family and is activated by p38 MAPK in response to several signals like mitogenic and stress stimuli. It has a crucial role in phosphorylating LIMK1 and hence plays a vital function in VEGF-A-induced actin reorganization, migration, and tubule formation of endothelial cells. Anti-MAP Kinase Activated Protein Kinase-2 (MAPKAPK-2) antibody can be used to study the differential tissue expression of MAPKAPK-2 and its intracellular localization in normal and neoplastic tissues. Rabbit anti-MAP Kinase Activated Protein Kinase-2 (MAPKAPK-2) antibody reacts specifically with human MAPKAPK-2protein (45 kD).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Anti-MAP Kinase Activated Protein Kinase-2 (MAPKAPK-2) antibody can be used in western blotting (diluted 1:2000) and microarray.

Price and Availability


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