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M4065 Sigma

Anti-Matrix Metalloproteinase-2 antibody produced in rabbit

~1 mg/mL, IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-MMP-2

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Adhesion, Attachment, and Matrix Factors, Antibodies against Adhesion/Attachment/Matrix Factors, Antibodies for Cell Biology,
species reactivity   rat, bovine, human, mouse
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 10-20 μg/mL
  western blot: 5-10 μg/mL
clone   polyclonal
concentration   ~1 mg/mL
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 72 kDa (proform)
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MMP2(4313)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide from the second half of human MMP-2 (Gelatinase-A, 72 kDa Gelatinase). The immunogen is synthesized as a 631 amino acid proenzyme that is activated by cleavage of the the first 80 amino acids.

Physical form

Solution in 10 mM phosphate buffered saline, pH 7.4, containing 0.2% bovine serum albumin and 0.09% sodium azide.

Specificity

Recognizes MMP-2, cytoplasmic localization. Shows no cross-reactivity with the pro and active forms of other MMPs.

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