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  • M4302 - Anti-Matrix Metalloproteinase-1, C-Terminal antibody produced in rabbit

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M4302 Sigma

Anti-Matrix Metalloproteinase-1, C-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-MMP-1

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Adhesion/Attachment/Matrix Factors, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
species reactivity   human
application(s)   western blot: 1:1,000 using a concentrated cell culture medium from a stimulated human cell line (M2928)
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MMP1(4312)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to C-terminal human matrix metalloproteinase-1 (interstitial collagenase).

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Specificity

By immunoblotting against the reduced protein, the antibody reacts with bands at 53 kDa and 51 kDa (the pro-form), as well as active forms. Also reacts with non-reduced MMP-1. Since the hemopexin domain is cleaved off to form the smallest active form of MMP-1, the antibody does not recognize the 21 kDa form of MMP-1.

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Safety Information

Symbol  GHS08  GHS08
Signal word  Danger
Hazard statements  H319-H334
Precautionary statements  P261-P305 + P351 + P338-P342 + P311
Personal Protective Equipment  Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  2
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