• USA Home
  • M4670 - D-Mannosamine hydrochloride

EMAIL THIS PAGE TO A FRIEND

M4670 Sigma

D-Mannosamine hydrochloride

Synonym: 2-Amino-2-deoxy-D-mannose hydrochloride

Purchase

Description

Packaging

1 g in poly bottle

100, 500 mg in poly bottle

10 mg in autosample vial

Application

D-Mannosamine hydrochloride can be used for the synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. 1 It has been used in a study to investigate the synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis. 2

Price and Availability


Mass Spectrometry Metabolite Library

Customers Also Viewed

Safety & Documentation

Safety Information

WGK Germany 
3

Protocols & Articles

Peer-Reviewed Papers

References

Set your institution to view full text papers.

1. Synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids Sampathkumar, S., et al. Nat. Protoc. 1, 2377-85, (2006)

Loading...


2. Synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis Liu, J., et al. J. Org. Chem. 69, 6273-83, (2004)

Loading...


Poly(anhydride) nanoparticles as adjuvants for mucosal vaccination. Irache JM, Salman HH, Gomez S, et al. Front. Biosci. (Schol. Ed.) 2, 876-90, (2010)

Loading...


Protein trafficking to the cell wall occurs through mechanisms distinguishable from default sorting in tobacco. De Caroli M, Lenucci MS, Di Sansebastiano GP, et al. Plant J. 65(2), 295-308, (2011)

Loading...


Conjunctival vaccination against Brucella ovis in mice with mannosylated nanoparticles. Da Costa Martins R, Gamazo C, Sánchez-Martínez M, et al. J. Control. Release 162(3), 553-60, (2012)

Loading...


Fluorescent live-cell imaging of metabolically incorporated unnatural cyclopropene-mannosamine derivatives. Cole CM, Yang J, Šečkutė J, et al. ChemBioChem. 14(2), 205-8, (2013)

Loading...


Inhibition of Neisseria meningitidis sialic acid synthase by a tetrahedral intermediate analogue. Liu F, Lee HJ, Strynadka NC, et al. Biochemistry 48(39), 9194-201, (2009)

Loading...


Improved sensitive high performance liquid chromatography assay for glucosamine in human and rat biological samples with fluorescence detection. Ibrahim A and Jamali F J. Pharm. Pharm. Sci. 13(2), 128-35, (2010)

Loading...


Immunoadjuvant capacity of flagellin and mannosamine-coated poly(anhydride) nanoparticles in oral vaccination. Salman HH, Irache JM, and Gamazo C Vaccine 27(35), 4784-90, (2009)

Loading...


Glycan-specific metabolic oligosaccharide engineering of C7-substituted sialic acids. Möller H, Böhrsch V, Bentrop J, et al. Angew. Chem. Int. Ed. Engl. 51(24), 5986-90, (2012)

Loading...


Coated cross-species antibodies by mannosamine-biotin adduct confer protection against snake venom without eliciting humoral immune response. Gefen T, Pitcovski J, Vaya J, et al. Vaccine 28(51), 8197-202, (2010)

Loading...


Babesia bovis contains an abundant parasite-specific protein-free glycerophosphatidylinositol and the genes predicted for its assembly. Rodríguez AE, Couto A, Echaide I, et al. Vet. Parasitol. 167(2-4), 227-35, (2010)

Loading...


Protecting group and solvent control of stereo- and chemoselectivity in glucal 3-carbamate amidoglycosylation. Gupta R, Sogi KM, Bernard SE, et al. Org. Lett. 11(7), 1527-30, (2009)

Loading...


A new route for the synthesis of Streptococcus pneumoniae 19F and 19A capsular polysaccharide fragments avoiding the beta-mannosamine glycosylation step. Bonaccorsi F, Catelani G, and Oscarson S Carbohydr. Res. 344(12), 1442-8, (2009)

Loading...


Efficient metabolic engineering of GM3 on tumor cells by N-phenylacetyl-D-mannosamine. Chefalo P, Pan Y, Nagy N, et al. Biochemistry 45(11), 3733-9, (2006)

Loading...


Sialic acid (N-acetyl neuraminic acid) utilization by Bacteroides fragilis requires a novel N-acetyl mannosamine epimerase. Brigham C, Caughlan R, Gallegos R, et al. J. Bacteriol. 191(11), 3629-38, (2009)

Loading...


Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations. Almaraz RT, Aich U, Khanna HS, et al. Biotechnol. Bioeng. 109(4), 992-1006, (2012)

Loading...


Metal chelation by the common 2-amino-2-deoxy-, 2-N-acetylamino-2-deoxy-, and 2-deoxy-hexoses. Schwarz T, Hess D, and Klüfers P Dalton Trans. 39(23), 5544-55, (2010)

Loading...


Efficient biotinylation of methacryloyl-functionalized nonadherent cells for formation of cell microarrays. Iwasaki Y and Ota T Chem. Commun. (Camb.) 47(37), 10329-31, (2011)

Loading...


High-throughput analysis of hexosamine using a colorimetric method. Cheng YS, Labavitch J, and VanderGheynst JS Anal. Biochem. 408(1), 160-2, (2011)

Loading...


Metabolic delivery of methacryloyl groups on living cells and cell surface modification via thiol-ene "click" reaction. Iwasaki Y and Matsuno H Macromol. Biosci. 11(11), 1478-83, (2011)

Loading...


Carbohydrate affinity chromatography indicates that arylsulfatase-A from capacitated boar sperm has mannose and N-acetylglucosamine/sialic acid residues. Jiménez I, Fierro R, González-Márquez H, et al. Arch. Androl. 52(6), 455-62, (2006)

Loading...


Mannosamine-biotin as a novel masking agent for coating IgG for immune response silencing and augmentation of antibody-antigen interaction. Vaya J, Aizenshtein E, Khatib S, et al. Vaccine 27(49), 6869-76, (2009)

Loading...


Extracellular and intracellular esterase processing of SCFA-hexosamine analogs: implications for metabolic glycoengineering and drug delivery. Mathew MP, Tan E, Shah S, et al. Bioorg. Med. Chem. Lett. 22(22), 6929-33, (2012)

Loading...


Development of mannosylated liposomes for bioadhesive oral drug delivery via M cells of Peyer's patches. Pukanud P, Peungvicha P, and Sarisuta N Drug Deliv. 16(5), 289-94, (2009)

Loading...


Practical preparation of 2-azido-2-deoxy-beta-D-mannopyranosyl carbonates and their application in the synthesis of oligosaccharides. Zhang J, Yan S, Liang X, et al. Carbohydr. Res. 342(18), 2810-7, (2007)

Loading...


Effects of hexosamines and omega-3/omega-6 fatty acids on pH regulation by interleukin 1-treated isolated bovine articular chondrocytes. Tattersall AL and Wilkins RJ Pflugers Arch. 456(3), 501-6, (2008)

Loading...


Beil. 4,IV,2022

FT-IR 2 (1), 547:B / RegBook 1 (1), 373:J / Sigma FT-IR 1 (1), 1098:C / Structure Index 1, 53:B:1

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?