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  • M4934 - Anti-Matrix Metalloproteinase-18, C-Terminal antibody produced in rabbit

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M4934 Sigma

Anti-Matrix Metalloproteinase-18, C-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-Xenopus collagenase, Anti-MMP-18, Anti-MMP-21-A, Anti-XMMP

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix, Antibodies to Matrix Metalloproteinases and TIMPs,
species reactivity   Xenopus
application(s)   immunohistochemistry (frozen sections): suitable
  immunoprecipitation: suitable
  indirect ELISA: suitable
  western blot: 1:1,000
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
Gene Information   Xenopus laevis ... mmp21-A(378572)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the C-terminal of Xenopus matrix metalloproteinase-18 (Xenopus collagenase, collagenase-4).

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Specificity

Reacts with reduced and non-reduced MMP-18. Recognizes pro-form and most active forms of MMP-18. When used against the reduced protein, the antibody identifies bands at 53 kDa and 51 kDa (pro-form) as well as the smaller activated forms. The hemopexin domain is cleaved form the smallest active form of MMP-18 and the antibody does not detect this form.

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