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  • M4937 - Anti-Melanocortin-3 Receptor antibody produced in rabbit

M4937 Sigma

Anti-Melanocortin-3 Receptor antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-MC3R



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Hormones, Antibodies to Pituitary Hormones,
species reactivity   rat, mouse (predicted)
application(s)   microarray: suitable
  western blot: 1:2,000 using rat brain homogenate extract
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 40 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   mouse ... Mc3r(17201)
rat ... Mc3r(29310)
biological source   rabbit
conjugate   unconjugated



A synthetic peptide corresponding to the N-terminal region of rat melanocortin receptor 3 (amino acids 15-33) coupled to keyhole limpet hemocyanin (KLH). This sequence is highly conserved in mouse MC3-R (89% identity).

General description

Melanocortins are regulatory peptides derived from post-translational processing of the larger pro-opiomelanocortin (POMC) precursor. Melanocortin-3 Receptor (MC3-R) is a 360 amino acid containing transmembrane protein that belongs to G-protein coupled receptor family and is expressed mainly in adult central nervous system at high levels in a restricted number of neurons of the hypothalamus and the limbic system. It has a crucial role in facilitating the effects of the melanocortin system on energy homeostasis. Anti-Melanocortin-3 Receptor antibody can be used in microarray. Rabbit anti-Melanocortin-3 Receptor antibody reacts specifically with rat MC3-R (40 kDa).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Anti-Melanocortin-3 Receptor antibody can be used in western blotting (diluted 1:2,000) using rat brain homogenate extract.

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