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  • M5028 - Monoclonal Anti-5MTH Folic Acid antibody produced in mouse

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M5028 Sigma

Monoclonal Anti-5MTH Folic Acid antibody produced in mouse

clone FA-24, ascites fluid

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Properties

Related Categories 1-A0, Alphabetical Index, Antibodies, Antibodies to Nuclear Proteins, Epigenetics,
biological source   mouse
antibody form   ascites fluid
clone   FA-24, monoclonal
contains   15 mM sodium azide
application(s)   indirect ELISA: 1:5,000
isotype   IgG2b
conjugate   unconjugated
shipped in   dry ice
storage temp.   −20°C

Description

Immunogen

5MTH folic acid, conjugated to KLH.

Application

Monoclonal Anti-5MTH Folic Acid antibody is suitable for use in indirect ELISA (1:5,000).

General description

5-Methyltetrahydrofolate (5-MTHF) is a cofactor that regulates the conversion of homocysteine to methionine in the presence of another co-factor, vitamin B12. 5-MTHF is also involved in modulating antioxidative and cognitive functions. Increased serum 5-MTHF levels have been linked to anemia and macrocytosis. Monoclonal Anti-5MTH Folic Acid antibody is specific for an epitope present on 5MTHFA and does not detect folic acid. The antibody reacts with 5MTHFA as a free reagent or when conjugated to carriers such as KLH or BSA. Furthermore, the product associates with 5MTHFA bound to the endogenous folate binder in human plasma and serum. The monoclonal antibody does not cross-react with tetrahydrofolic acid, folinic acid, dihydrofolic acid, and vitamin B12.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
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Peer-Reviewed Papers
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