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M5250 Sigma

Melatonin

powder, ≥98% (TLC)

Synonym: N-Acetyl-5-methoxytryptamine

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Description

Caution

Solutions are light sensitive and subject to oxidation.

Packaging

1, 5, 10 g in glass bottle

250 mg in glass bottle

Biochem/physiol Actions

Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability


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Safety & Documentation

Safety Information

WGK Germany 
2
RTECS 
AC5955000
Protocols & Articles

Articles

MSMLS Online Plate Map

MSMLS compounds are conveniently provided at 5μg per well, enough for multiple injections. These are high purity (>95%) compounds supplied in an economical, ready to use format. Compounds are arrange...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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