|Related Categories||4-4B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix,|
|species reactivity||mouse, rat, monkey, hedgehog, rabbit, pig, human, feline, chicken|
|immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200 using sections of human stomach|
|western blot: suitable using non-reducing conditions|
|antibody form||ascites fluid|
|contains||15 mM sodium azide|
|shipped in||dry ice|
human ... MUC5AC(4586)|
mouse ... Muc5ac(17833)
rat ... Muc5ac(65188)
mucin from human ovarian cyst fluid.
The antibody recognizes the mucin epitope g located in the peptide core of gastric mucin (>1,000 kDa). This epitope is completely destroyed by thiol reduction (using mercaptoethanol) and partially lost following trypsin proteolysis, but is stable upon periodate oxidation. The antibody stains the surface gastric epithelium of normal human gastrointestinal tract and reacts with fetal, pre-cancerous and cancerous colonic mucosa, but not with normal colon.
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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