• USA Home
  • M5525 - 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester

EMAIL THIS PAGE TO A FRIEND
M5525 Sigma

4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester

≥98%, powder

Synonym: N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate, SMCC

Purchase

Properties

Related Categories Amine to Sulfhydryl, Chemical Biology, Chemical Synthesis, Crosslinkers, Crosslinking,
InChI Key   JJAHTWIKCUJRDK-UHFFFAOYSA-N
assay   ≥98%
form   powder
mp   180-182 °C(lit.)
solubility   chloroform: soluble50 mg/mL
  DMF: soluble
shipped in   wet ice
storage temp.   −20°C

Description

Application

A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.

Packaging

25, 100 mg in poly bottle

5 mg in glass bottle

Price and Availability


Amplified Detection

Amicon Pro Purification System
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?