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M5534 Sigma

IgG2b Isotype Control from murine myeloma

clone MOPC-141, purified immunoglobulin, buffered aqueous solution

Synonym: Mouse IgG2b, κ

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Properties

Related Categories Analytical Cytology, Antibodies, Antibody Characterization and Analysis, Biochemicals and Reagents, Isotype Controls,
biological source   mouse
antibody form   purified immunoglobulin
clone   MOPC-141, monoclonal
form   buffered aqueous solution
application(s)   flow cytometry: suitable
isotype   IgG2bκ
conjugate   unconjugated
shipped in   wet ice
storage temp.   2-8°C

Description

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Application

IgG2b Isotype Control is suitable for use in ELISA and flow cytometry.

General description

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . IgG2b Isotype Control is specific for anti-mouse whole serum, IgG2b, and κ chain. The product does not react with antisera to mouse λ light chain, IgA, IgM, IgG1, IgG2a, and IgG3.

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Detect Your Unseen Protein
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

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