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M5925 Sigma

NA2 Glycan

from human fibrinogen, ≥90%

Synonym: (Gal-GlcNAc)2Man3(GlcNAc)2, Mannotriose-di-(N-acetyl-D-glucosamine), bis(galactosyl-[N-acetyl-D-glucosaminyl])

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Properties

Related Categories Glycan Component Classes, Glycobiology, Molecular Biology, N-Glycans, N-Linked Complex Glycans,
biological source   from human fibrinogen
InChI Key   JMUPMJGUKXYCMF-IWDIICGPSA-N
assay   ≥90%
storage temp.   −20°C

Description

General description

Many of the key molecules involved in the innate and adaptive immune response are glycoproteins

Application

NA2 Glycan has been used in a study to assess the electron detachment dissociation of neutral and sialylated oligosaccharides. It has also been used in a study to investigate the interplay of permanent charge and hydrophobicity in the electrospray ionization of glycans.

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Glycan Standards

The analysis of the glycan portion of glycoproteins is necessary for monitoring changes in post-translational modification that occur in disease states, as well as evaluating the consistency of glyco...
BioFiles 2007, 2.1, 18.
Keywords: Applications, Biofiles, Chromatography, Digestions, Electrophoresis, Gel electrophoresis, Gene expression, Glycosylations, High performance liquid chromatography, Mass spectrometry, N-linked glycosylation, Phase transitions, Post translational modifications, Purification, Separation, Sequencing

N-Linked Glycans

N-linked glycosylation, modification, and degradation are involved in a wide variety of processes in all organisms from archaea to eukaryotes. It is the most common covalent protein modification in e...
Glycobiology Analysis Manual, 2nd Edition
Keywords: Catalysis, Degradations, Diseases, Eliminations, Fucosylation, Glycosylations, Metabolism, N-linked glycosylation, Sequences, Substitutions, Type, transformation

Peer-Reviewed Papers
15

References

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