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  • M6184 - Anti-Matrix Metalloproteinase-23, C-Terminal antibody produced in rabbit

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M6184 Sigma

Anti-Matrix Metalloproteinase-23, C-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-MMP-23

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix, Antibodies to Matrix Metalloproteinases and TIMPs,
species reactivity   human
application(s)   immunohistochemistry (frozen sections): suitable
  immunoprecipitation: suitable
  indirect ELISA: suitable
  western blot: 1:1,000
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antigen (active form) mol wt 45 kDa
  antigen (pro-form) mol wt 58 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MMP23B(8510)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the C-terminal of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).

General description

Matrix metalloproteinase-23B (MMP-23B) possesses regions which are rich in amino acids like proline and cysteine. The MMP-23B gene is localized on human chromosome 1p36.

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Specificity

Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms. The hemopexin domain is removed from the smallest active form of MMP-23 and the antibody does not detect this form.

Biochem/physiol Actions

Matrix metalloproteinase-23B (MMP-23B) is part of the matrix metalloproteinase family of proteins, which take part in the remodeling of the extracellular matrix.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  1
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Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

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