• USA Home
  • M6518 - Macrophage Colony-Stimulating Factor human

M6518 Sigma

Macrophage Colony-Stimulating Factor human

M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym: MCSF



Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines as adjuvants,
recombinant   expressed in E. coli
assay   ≥98% (SDS-PAGE and HPLC)
form   lyophilized powder
quality   endotoxin tested
mol wt   dimer mol wt 37 kDa
suitability   suitable for cell culture
storage temp.   −20°C


Analysis Note

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

Biochem/physiol Actions

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

Other Notes

159 amino acids including N-terminal methionine (each monomer).

Physical form

Lyophilized from a sterile filtered buffered solution.

Price and Availability

Polymeric Drug Delivery Techniques Guide

Learn about PharmaGrade

Customers Also Viewed

GM-CSF, recombinant, expressed in E. coli, suitable for cell culture

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested

Macrophage Colony-Stimulating Factor from mouse

M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

M-CSF, recombinant, expressed in HEK 293 cells, suitable for cell culture

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested

Safety & Documentation

Safety Information

WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers


Set your institution to view full text papers.

Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response. Bayry J, Beaussart A, Dufrêne YF, et al. Infect. Immun. 82(8), 3141-53, (2014)


Radioprotection of hematopoietic progenitors by low dose amifostine prophylaxis. Seed TM, Inal CE, Singh VK, et al. Int. J. Radiat. Biol. 90(7), 594-604, (2014)


Expressional changes of genes and miRNA in common megakaryocyte-erythroid progenitors from lower-risk myelodysplastic syndrome. Maki K, Sasaki K, Nagata Y, et al. Int. J. Hematol. 100(4), 361-9, (2014)


Bordetella pertussis proteins dominating the major histocompatibility complex class II-presented epitope repertoire in human monocyte-derived dendritic cells. Stenger RM, Meiring HD, Kuipers B, et al. Clin. Vaccine Immunol. 21(5), 641-50, (2014)


Induction of murine macrophage M2 polarization by cigarette smoke extract via the JAK2/STAT3 pathway. Yuan F, Fu X, Shi H, et al. PLoS ONE 9(9), e107063, (2014)


Activation of GILZ gene by photoactivated 8-methoxypsoralen: potential role of immunoregulatory dendritic cells in extracorporeal photochemotherapy. Futterleib JS, Feng H, Tigelaar RE, et al. Transfus. Apher. Sci. 50(3), 379-87, (2014)


The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently. Józefowski S, Biedro? R, Sróttek M, et al. Innate Immunity 20(8), 826-47, (2014)


Dendritic cells transfected with hepatocellular carcinoma (HCC) total RNA induce specific immune responses against HCC in vitro and in vivo. Xie BH, Yang JY, Li HP, et al. Clin. Transl. Oncol. 16(8), 753-60, (2014)


Macrophage-specific lipid-based nanoparticles improve cardiac magnetic resonance detection and characterization of human atherosclerosis. Lipinski MJ JACC. Cardiovasc. Imaging 2(5), 637-47, (2009)


Related Products

related product

Product #


Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?