• USA Home
  • M6559 - Anti-Matrix Metalloproteinase-24, Cytoplasmic antibody produced in rabbit

M6559 Sigma

Anti-Matrix Metalloproteinase-24, Cytoplasmic antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-MMP-24, Anti-MT5-MMP


Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix, Antibodies to Matrix Metalloproteinases and TIMPs,
species reactivity   mouse, human
application(s)   flow cytometry: suitable
  immunohistochemistry (frozen sections): suitable
  immunoprecipitation: suitable
  indirect ELISA: suitable
  western blot: 1:2,000
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antigen mol wt 65 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MMP24(10893)
mouse ... Mmp24(17391)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to the cytoplasmic domain of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5)

General description

Matrix metalloproteinase-24 (MMP-24) is mainly expressed in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.


Reacts with native and reduced MMP-24. The antibody recognizes the pro-form of MMP-24 as well as activation/breakdown products. The cytoplasmic domain of MMP-24 is detached when MT-MMPs shed from themselves, thus this antibody should not detect this form of MMP-24.

Biochem/physiol Actions

Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.

Price and Availability

Detect Your Unseen Protein

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?