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M6661 Sigma

MPL® + TDM + CWS Adjuvant


Synonym: Monophosphoryl-lipid A + Trehalose dicorynomycolate + Cell wall skeleton adjuvant



Related Categories Adjuvant Reagents, Antibodies, Antibody Purification and Characterization, Supplementary Products
form   oil
storage temp.   2-8°C


General description

Each vial contains 0.5 mg monophosphoryl lipid A from S. minnesota (MPL), 0.5 mg trehalose dicorynomycolate (TDM) and 0.5 mg cell wall skeleton from a tubercule bacillus (CWS) in 2% oil-Tween 80-water. The CWS provides additional immunopotentiating activity.


Ribi Adjuvant System (RAS) for use in rabbits, goats and larger animals.
RAS is a stable oil-in-water emulsion that may be used as an alternative to the water-in-oil emulsions. These adjuvants are derived from bacterial and mycobacterial cell wall components that have been prepared to reduce the undesirable side effects of toxicity and allergenicity, but still provide potent stimulus to the immune system.

Legal Information

MPL is a registered trademark of Corixa Corporation

Price and Availability

Amplified Detection
Safety & Documentation

Safety Information

WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Related Content

Antibody Explorer - Search 80,000 Antibodies at Sigma-Aldrich

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


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