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M6807 Sigma

Misoprostol

≥99% (HPLC)

Synonym: (±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester

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Properties

Related Categories Arachidonic Acid Cascade, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Eicosanoids (Prostaglandins, Leukotrienes),
InChI Key   OJLOPKGSLYJEMD-URPKTTJQSA-N
assay   ≥99% (HPLC)
storage temp.   −20°C
Gene Information   human ... PTGIR(5739)

Description

Biochem/physiol Actions

Cytoprotective PGE1 analog that prevents NSAID-induced gastric ulceration.

PGE1 analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2810 6.1 / PGIII
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

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