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  • M6908 - Myeloperoxidase from human leukocytes


M6908 Sigma

Myeloperoxidase from human leukocytes

lyophilized powder, ≥50 units/mg protein

Synonym: MPO, Peroxidase, myelo


Related Categories 1.11.x.x Peroxide as receptor, 1.x.x.x Oxidoreductases, Application Index, Biochemicals and Reagents, Cell Biology,
form   lyophilized powder
solubility   H2O: soluble
  aqueous buffers such as 50 mM sodium acetate: soluble (Freezing of the enzyme in solution may result in a substantial loss of activity.)
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MPO(4353)


Analysis Note

Source material tested and found negative for antibody to HIV and for HBSAG.

Biochem/physiol Actions

Catalyzes oxidations by hydrogen peroxide, including cytotoxic actions on bacteria, fungi, and tumor cells. Also catalyzes cross-linking of immune complexes and inactivates chemotactic factors.

Other Notes

Lysosomal heme-containing protein.

Unit Definition

One unit will produce an increase in absorbance (A470) of 1.0 per min at pH 7.0 and 25 °C, calculated from the initial rate of reaction using guaiacol as substrate. Total reaction volume: 3.035 mL.

Physical form

Lyophilized from 50 mM sodium acetate buffer, pH 6.0, 0.1 M sodium chloride

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Metabolomic Pathways Chart

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