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M6908 Sigma

Myeloperoxidase from human leukocytes

lyophilized powder, ≥50 units/mg protein

Synonym: MPO, Peroxidase, myelo

Properties

Related Categories 1.11.x.x Peroxide as receptor, 1.x.x.x Oxidoreductases, Application Index, Biochemicals and Reagents, Cell Biology,
form   lyophilized powder
solubility   H2O: soluble
  aqueous buffers such as 50 mM sodium acetate: soluble (Freezing of the enzyme in solution may result in a substantial loss of activity.)
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MPO(4353)

Description

Analysis Note

Source material tested and found negative for antibody to HIV and for HBSAG.

Biochem/physiol Actions

Catalyzes oxidations by hydrogen peroxide, including cytotoxic actions on bacteria, fungi, and tumor cells. Also catalyzes cross-linking of immune complexes and inactivates chemotactic factors.

Other Notes

Lysosomal heme-containing protein.

Unit Definition

One unit will produce an increase in absorbance (A470) of 1.0 per min at pH 7.0 and 25 °C, calculated from the initial rate of reaction using guaiacol as substrate. Total reaction volume: 3.035 mL.

Physical form

Lyophilized from 50 mM sodium acetate buffer, pH 6.0, 0.1 M sodium chloride

Price and Availability


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