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  • M6934 - Anti-Matrix Metalloproteinase-24, Propeptide Region antibody produced in rabbit

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M6934 Sigma

Anti-Matrix Metalloproteinase-24, Propeptide Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-MMP-24, Anti-MT5-MMP

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix, Antibodies to Matrix Metalloproteinases and TIMPs,
species reactivity   mouse, human
application(s)   flow cytometry: suitable
  immunohistochemistry (frozen sections): suitable
  immunoprecipitation: suitable
  indirect ELISA: suitable
  western blot: 1:2,000
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antigen mol wt 65 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MMP24(10893)
mouse ... Mmp24(17391)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the propeptide region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5).

General description

Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide

Specificity

Reacts with reduced and native MMP-24. Recognizes only the pro-form of MMP-24 and not the active forms.

Biochem/physiol Actions

Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.

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Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

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