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M7184 Sigma

Matrix Metalloproteinases and TIMPs

  •  ISBN-10 0-19-850268-0

  •  ISBN-13 978-0-19-850268-5

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Related Categories Application Index, Biochemicals and Reagents, Biochemistry Books, Books and Software, Cell Signaling Enzymes,
publication info   J.F. Woessner and H. Nagase, ed., Oxford University Press, 2000, 240 pp., soft cover
mfr. no.   Oxford University Press

Description

General description

This book contains comprehensive data about matrix metalloproteinases (MMPs), enzymes which break down the extracellular matrix. It covers their sequences, three-dimensional structure, activation, substrates, specificity, inhibition, biological roles and function, along with protein sequence alignments. MMPs are regulated by their inhibitors (TIMPs). This volume contains sequences, three-dimensional structures and biological roles of TIMPs along with over 1700 references on MMPs and TIMPs.

Table of Contents

Abbreviations; Introduction; MMP sequences; TIMP sequences; Three dimensional structures of the MMPs and TIMPs; Activation of the zymogen forms of MMPs; Protein substrates of the MMPs; Specificity requirements of the MMPs; Inhibition of the MMPs; Biological roles of the MMPs; Biological roles of the TIMPs; Bibliography; Protein sequence alignments

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