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M7195 Sigma

Anti-MO25 (C-terminus) antibody produced in rabbit

~2 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym: Anti-CAB39, Anti-CGI-66, Anti-Calcium binding protein 39

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Intracellular Calcium Signaling, Antibodies to Calcium-Associated Proteins,
species reactivity   human, rat (predicted), mouse (predicted)
application(s)   western blot: 0.5-1 μg/mL using HEK-293T cells expressing human MO25 and PC12 cell lysates
clone   polyclonal
concentration   ~2 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt ~40 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CAB39(51719)
mouse ... Cab39(12283)
rat ... Cab39(301574)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 323-341 located near the C-terminus of human MO25. This sequence is identical in chicken, dog, and bovine MO25 and highly conserved in rat and mouse MO25 (2 amino acid substitutions).

General description

MO25 is a 40 kDa scaffolding protein that interacts with STRADα and LKB1 to regulate tumor suppression. MO25 also facilitates the activation and cytoplasmic localization of LKB1 . Anti-MO25 (C-terminus) antibody detects human MO25 (approx. 40 kDa). The product is also predicted to react with rat and mouse MO25. Staining of the MO25 band in immunoblotting is specifically inhibited by the immunizing peptide.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

Application

Anti-MO25 (C-terminus) antibody is suitable for use in western blot (0.5-1 μg/mL using HEK-293T cells expressing human MO25 and in PC12 cell lysates).

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WGK Germany  3
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M7070 Anti-MO25 antibody produced in rabbit, ~2 mg/mL, affinity isolated antibody, buffered aqueous solution

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