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  • M7398 - Monoclonal Anti-β2-Microglobulin antibody produced in mouse

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M7398 Sigma

Monoclonal Anti-β2-Microglobulin antibody produced in mouse

clone BM-63, ascites fluid

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Properties

Related Categories Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood,
species reactivity   human
application(s)   indirect ELISA: 1:1000
  indirect immunofluorescence: 1:500 using human PBL′s
clone   BM-63, monoclonal
antibody form   ascites fluid
isotype   IgG1
mol wt   antigen mol wt 12 kDa
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... B2M(567)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

human β2-microglobulin and a lysate of a lymphoblastoid cell line.

General description

β-2-microglobulin is part of the human leukocyte antigen, where it represents the light chain. It is expressed on cell membranes and is made up of 99 amino acids. β-2-microglobulin is part of the immunoglobulin superfamily.

Antigen Background

β2-Microglobulin is a membrane glycoprotein of mammalian nucleated cells including lymphocytes and may function as a structural part of the MHC Class I molecule.

Biochem/physiol Actions

β-2-microglobulin acts as a tumor marker and has been shown to be associated with dialysis-related amyloidosis.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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Peer-Reviewed Papers
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