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M7765 Sigma

1-Oleoyl-rac-glycerol

≥99%

Synonym: 1-(cis-9-Octadecenoyl)-rac-glycerol, rac-Glycerol 1-monooleate, DL-α-Monoolein, Glyceryl cis-9-octadecenoate, Monoolein

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Description

Biochem/physiol Actions

Monoolein (1-Oleoyl-rac-glycerol) is used in the development of monoolein-based nanoparticulate liquid dispersions as possible vehicles for drug delivery.

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European Pharmacopoeia (EP) Reference Standard

Safety & Documentation

Safety Information

WGK Germany 
1
Flash Point(F) 
309.2 °F
Flash Point(C) 
154 °C

Protocols & Articles

Peer-Reviewed Papers

References

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Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity. Hyeun Wook Chang et al Bioorg. Med. Chem. Lett. 18, 3589-92, (2008)

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Initial step of pH-jump-induced lamellar to bicontinuous cubic phase transition in dioleoylphosphatidylserine/monoolein. Oka T, Tsuboi TA, Saiki T, et al. Langmuir 30(27), 8131-40, (2014)

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Nanoparticulate lipid dispersions for bromocriptine delivery: characterization and in vivo study. Esposito E, Mariani P, Ravani L, et al. Eur. J. Pharm. Biopharm. 80, 306-314, (2012)

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Complex dendrimer-lyotropic liquid crystalline systems: structural behavior and interactions. Bitan-Cherbakovsky L, Libster D, et al. J. Phys. Chem. B 115, 11984-11992, (2011)

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Aggregation behavior of aqueous dioctadecyldimethylammonium bromide/monoolein mixtures: A multitechnique investigation on the influence of composition and temperature. Oliveira IM, Silva JP, Feitosa E, et al. J. Colloid. Interface Sci. 374, 206-217, (2012)

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A two-stage enzymatic process for synthesis of extremely pure high oleic glycerol monooleate. Zhu Q, Li T, Wang Y, Yang B, Ma Y. Enzyme Microb. Technol. 48, 143-147, (2011)

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Preparation, characterization and physico-chemical properties of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC): their benefits as colloidal drug carrier systems. Uner M. Pharmazie 61, 375-386, (2006)

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Monoolein lipid phases as incorporation and enrichment materials for membrane protein crystallization. Wallace E, Dranow D, Laible PD, et al. PLoS ONE 6, e24488, (2011)

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Beil. 2,IV,1657

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