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M7931 Sigma

Monoclonal Anti-Mcm7 antibody produced in mouse

clone DCS-141, ascites fluid

Synonym: Anti-Cdc47

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Cell Cycle, Antibodies to Check Point Proteins,
species reactivity   human, Xenopus
application(s)   immunocytochemistry: suitable
  immunoprecipitation: suitable
  western blot: 1:2,000 using HeLa cell nuclear preparation
clone   DCS-141, monoclonal
antibody form   ascites fluid
isotype   IgG1
mol wt   antigen mol wt ~80 kDa
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MCM7(4176)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

recombinant human Mcm7 (Cdc47) protein

General description

Minichromosome maintenance complex component 7 (MCM7) is part of the pre-replication complex.

Antigen Background

Mcm7 (Cdc47) belongs to the minichromosome maintenance family.

Specificity

Recognizes human Mcm7 and also a weaker lower molecular weight doublet.

Biochem/physiol Actions

Minichromosome maintenance complex component 7 (MCM7) has been shown to possess DNA helicase activity and is crucial for initiating replication.

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