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  • M8430 - Anti-Matrix Metalloproteinase-8, Propeptide Region antibody produced in rabbit

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M8430 Sigma

Anti-Matrix Metalloproteinase-8, Propeptide Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-MMP-8

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Extracellular Matrix, Antibodies to Matrix Metalloproteinases and TIMPs,
species reactivity   human
application(s)   western blot (chemiluminescent): 1:5,000
  western blot: 1:1,000
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antigen mol wt 85 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MMP8(4317)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-8 (neutrophil collagenase, collagenase-2).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

Specificity

Reacts with reduced and non-reduced latent MMP-8. The propeptide region is shed after activation; therefore, the antibody recognizes only the latent form of MMP-8. May be used to distinguish between latent and active MMP-8.

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