Synonym: d-Desoxyephedrine hydrochloride, d-N,α-Dimethylphenethylamine hydrochloride, Methylamphetamine hydrochloride
|Related Categories||Amphetamine, Analytical Standards, Analytical/Chromatography, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules,|
|drug control||USDEA Schedule II; Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada|
Sympathomimetic with more potent central effects than amphetamine. It is transported into terminals via the monoamine transporters and induces release of dopamine, norepinephrine, epinephrine, and serotonin. Dopamine release is important for the addictive properties of methamphetamine while norepinephrine and epinephrine release are important for the cardiovascular effects. Serotonin neurotoxin.
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analytical standard, for drug analysis, 1.0 mg/mL±5% in methanol
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P301 + P310|
|Personal Protective Equipment||Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||25|
|Safety Statements (Europe)||45|
|RIDADR||UN 2811 6.1 / PGIII|
Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: a pharmacological strategy for treating stimulant abuse. Rothman, R.B., et al. Synapse 35, 222-227, (2000)
Serotonin 2 Receptor Modulation Of Hyperthermia, Corticosterone, And Hippocampal Serotonin Depletions Following Serial Exposure To Chronic Stress And Methamphetamine. Doyle, J.R., and Yamamoto, B.K. Psychoneuroendocrinology 35, 629-33, (2010)
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