• USA Home
  • M9434 - Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat

EMAIL THIS PAGE TO A FRIEND
M9434 Sigma

Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat

clone 14, tissue culture supernatant

Synonym: Anti-MBP

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neural Stem Cells, Antibodies for Neurobiology,
species reactivity   guinea pig, bovine, human, sheep, rabbit (weak)
application(s)   immunohistochemistry: suitable
  indirect ELISA: suitable
clone   14, monoclonal
antibody form   tissue culture supernatant
isotype   IgG
contains   0.09% sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MBP(4155)
biological source   rat
conjugate   unconjugated

Description

Immunogen

bovine myelin basic protein.

General description

Myelin basic protein (MBP) is part of the myelin sheath and is a calcium-dependent protein. It has six isoforms and the gene encoding it is localized on human chromosome 18q23.

Specificity

Recognizes amino acids 36-50 of myelin basic protein.

Preparation Note

Generated by somatic cell hybridization of NS0 myeloma cells with spleen cells from an outbred rat immunized with bovine myelin basic protein.

Biochem/physiol Actions

Myelin basic protein (MBP) associates with calmodulin and has been identified as an auto-antigen in multiple sclerosis (MS). It also inhibits the assembly of amyloid-β protein.

Price and Availability


Antibody Explorer

Explore with Confidence

All labs need water
Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

RIDADR  NONH for all modes of transport
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

M0571 MBP (85-99) peptide antagonist trifluoroacetate salt, 95% (HPLC), lyophilized powder
M3821 Anti-Myelin Basic Protein (MBP) antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?