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M9557 Sigma

Anti-Macrophage Inflammatory Protein-3β antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-MIP-3β

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Chemokines, Antibodies to Cytokines and Growth Factors,
species reactivity   mouse
application(s)   immunocytochemistry: 5-15 μg/mL
  neutralization: 0.8-4 μg/mL
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   mouse ... Ccl19(24047)
biological source   goat
conjugate   unconjugated

Description

Immunogen

Recombinant mouse MIP-3β, expressed in Escherichia coli.

General description

The antibody neutralizes the biological activity of recombinant mouse MIP-3β. Using 50 times more, the antibody will neutralize the biological activity of recombinant human MIP-3β. The antibody shows 5% cross-reactivity with recombinant human MIP-3β.

Physical form

Lyophilized from a 0.2 μm-filtered solution in phosphate-buffered saline containing carbohydrates.

Biochem/physiol Actions

Macrophage Inflammatory Protein-3β is a chemokine that facilitates the migration of dendritic cells and antigen-presenting cells. It interacts with specific G protein-coupled seven-transmembrane domain chemokine receptor, CCR7 and promotes interactions between T cells and dendritic cells and migration of activated B cells to lymphoid tissues.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
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References

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