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N0399 Sigma

Anti-Nix antibody produced in rabbit

1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym: Anti-BNIP3α, Anti-BNIP3L

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Bcl-2 Family Proteins,
species reactivity   human, mouse
application(s)   western blot: 0.5-1 μg/mL using a K562 cell lysate.
clone   polyclonal
concentration   1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 38 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... BNIP3L(665)
mouse ... Bnip3l(12177)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 77-92 of an internal domain of human Nix. This peptide is identical in mouse.

General description

BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L) is expressed in the outer membrane of mitochondria. The BNIP3L gene is localized on human chromosome 8p21.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L) associates with proteins which are anti-apoptotic, like B-cell lymphoma 2 (Bcl-2). It also takes part in the growth of the erythroid lineage. Expression of BNIP3L is downregulated in lung cancer cells in vitro.

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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  nwg
Protocols & Articles

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Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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