Skip to Content
MilliporeSigma

N0756

N-Nitrosodiethylamine

liquid, nitrosamine

Synonym(s):

Diethylnitrosamine

Sign In to View Organizational & Contract Pricing

Select a Size

N0756-10ML

$191.00

N0756-25ML

$421.00

$191.00


Available to ship TODAYDetails


Request a Bulk Order

About This Item

Linear Formula:
(C2H5)2NNO
CAS Number:
Molecular Weight:
102.14
Beilstein/REAXYS Number:
1744991
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N-Nitrosodiethylamine, liquid

form

liquid

Quality Level

color

yellow

bp

177 °C (lit.)

density

0.95 g/mL (lit.)

SMILES string

CCN(CC)N=O

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI key

WBNQDOYYEUMPFS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
73861N0258442687
form

liquid

form

liquid

form

liquid

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

color

yellow

color

-

color

-

color

-

bp

177 °C (lit.)

bp

177 °C (lit.)

bp

177 °C (lit.)

bp

177 °C (lit.)

density

0.95 g/mL (lit.)

density

0.95 g/mL (lit.)

density

0.95 g/mL (lit.)

density

0.95 g/mL (lit.)

General description

N-Nitrosodiethylamine belongs to the nitrosamines category of nitrogenous disinfection byproduct. It is also generated in chlorine based water treatment plants.[1]

Application

N-Nitrosodiethylamine has been used to induce hepatocarcinogenesis in rat[2][3] and mice.[4]

Biochem/physiol Actions

N-Nitrosodiethylamine (NDMA) is carcinogenic in all animal species tested. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.[5] NDMA is acted upon by the cytochrome P450 system resulting in the formation of carcinogenic methyldiazonium ion. However microbes like Pseudomonas metabolize NDMA into N-nitromethylamine (NTMA) and formaldehyde.[6]

Packaging

Bulk Package

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Smyd3 is a transcriptional potentiator of multiple cancer-promoting genes and required for liver and colon cancer development
Sarris ME, et al.
Cancer Cell, 29(3), 354-366 (2016)
Jun Ho Lee et al.
EBioMedicine, 58, 102926-102926 (2020-08-03)
High recurrence and chemoresistance drive the high mortality in hepatocellular carcinoma (HCC). Although cancer stem cells are considered to be the source of recurrent and chemoresistant tumors, they remain poorly defined in HCC. Tonicity-responsive enhancer binding protein (TonEBP) is elevated
Occurrence and control of N-nitrosodimethylamine in water engineering systems
Bian Y, et al.
Environmental Engineering Research, 24(1), 1-16 (2018)
Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis
Choiniere J, et al.
Liver research, 2(2), 100-107 (2018)
Effects of heavy metal ions on N-nitrosodimethylamine (NDMA) formation
Liu Y, et al.
Royal Society of Chemistry Advances, 6(74), 70474-70479 (2016)

Articles

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.

Questions

1–2 of 2 Questions  
  1. Bei welcher Temperatur muss N0756 gelagert werden? Vielen Dank.

    1 answer
    1. This product may be stored in room temperature.

      Helpful?

  2. What is the concentration of product N0756?

    1 answer
    1. The concentration of product N0756 is 9.3 M, calculated using a density of 0.95 g/mL and a molecular weight of 102.14 g/mole.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service