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N135 Sigma

S(+)-Niguldipine hydrochloride

solid

Synonym: S(+)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(4,4-diphenyl-1-piperidinyl)-propyl methyl ester hydrochloride

  • CAS Number 113165-32-5

  • Empirical Formula (Hill Notation) C36H39N3O6 · HCl

  • Molecular Weight 646.17

  •  MDL number MFCD00873564

  •  PubChem Substance ID 24897482

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Properties

Related Categories Adrenergics, Adrenergics - Antagonists, Antagonists, Biochemicals and Reagents, Cell Biology,
InChI Key   MHOSUIMBPQVOEU-WAQYZQTGSA-N
form   solid
optical activity   [α]22/D +14.62°, c = 0.13 in methanol(lit.)
color   yellow
solubility   DMSO: soluble13 mg/mL
  ethanol: soluble16 mg/mL
  methanol: soluble8 mg/mL
  H2O: insoluble
  dilute aqueous acid: insoluble
storage temp.   −20°C

Description

Caution

Photosensitive. This compound adsorbs strongly to plastic.

Biochem/physiol Actions

α1A-adrenoceptor antagonist; antihypertensive agent; L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channels.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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