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N156 Sigma

Naltriben methanesulfonate hydrate

≥98% (HPLC), solid

Synonym: NTB hydrate

  • Empirical Formula (Hill Notation) C26H25NO4 · CH4O3S · xH2O

  • Molecular Weight 511.59 (anhydrous basis)

  •  MDL number MFCD11046015

  •  PubChem Substance ID 24278045

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Description

Biochem/physiol Actions

Naltriben methanesulfonate is a highly selective δ2 opioid receptor antagonist. The relative ability of the delta antagonists benzylidenenaltrexone and naltriben to inhibit DPDPE-stimulated [35S]GTPgammaS binding suggests that the opioid receptor is of the delta-2 subtype. Ligand binding assays demonstrates biphasic binding of the antagonist to the single receptor type. [35S]GTPgammaS binding is also stimulated by [D-Ser2,Leu5,Thr6]enkepha

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
PB9175000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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