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N179 Sigma

NS 102

solid

Synonym: 6,7,8,9-Tetrahydro-5-nitro-1H-benz[g]indole-2,3-dione 3-oxime

  • CAS Number 136623-01-3

  • Empirical Formula (Hill Notation) C12H11N3O4

  • Molecular Weight 261.23

  •  PubChem Substance ID 24897529

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Properties

Related Categories AMPA/Kainate Antagonists, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels,
InChI Key   SCDBMLHUXJBJSS-UHFFFAOYSA-N
form   solid
color   yellow
solubility   DMSO: >3 mg/mL
  H2O: insoluble
  methanol: insoluble
Gene Information   human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

Description

Biochem/physiol Actions

Competitive glutamate receptor antagonist with high selectivity for the low-affinity [3H] kainate binding site.

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Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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