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N2255 Sigma

S-(4-Nitrobenzyl)-6-thioinosine

≥98%, solid

Synonym: 6-[(4-Nitrobenzyl)thio]-9-β-D-ribofuranosylpurine, NBMPR, NBTI

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Properties

Related Categories Adenosines/P2 Nucleotide Receptors (Purinergics), Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission,
InChI Key   DYCJFJRCWPVDHY-LSCFUAHRSA-N
assay   ≥98%
form   solid
color   white
mp   187-190 °C(lit.)
solubility   0.1 M HCl: slightly soluble
  0.1 M NaOH: slightly soluble
  DMSO: soluble
  H2O: insoluble
storage temp.   2-8°C
Gene Information   human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), SLC29A1(2030)

Description

Biochem/physiol Actions

Potent adenosine uptake inhibitor

Inhibitor of equilibrative nucleoside transporters (ENTs), particularly adenosine transporters, in central nervous system and vascular smooth muscle.

Packaging

100, 250 mg in poly bottle

25 mg in glass bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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