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  • N2643 - Anti-Nitric Oxide Synthase, Endothelial (596-609) antibody produced in rabbit

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N2643 Sigma

Anti-Nitric Oxide Synthase, Endothelial (596-609) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-eNOS

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Cell Stress, Antibodies for Nitric Oxide Research,
species reactivity   bovine, human, mouse
application(s)   immunohistochemistry (frozen sections): 1:100 using acetone-fixed, frozen tissue sections of mouse heart
  microarray: suitable
  western blot: 1:10,000 using bovine lung endothelial cell extract
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... NOS3(4846)
mouse ... Nos3(18127)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to nitric oxide synthase (NOS) of bovine endothelial origin (eNOS, amino acids 596-609) conjugated to KLH. The immunogen sequence is identical in human eNOS.

General description

The gene encoding endothelial nitric oxide synthase (eNOS) is localized on human chromosome 7q35-36 and has 26 exons.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Biochem/physiol Actions

Endothelial nitric oxide synthase (eNOS) is a modulator of vascular function and it is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated coronary artery disease.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
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Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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