β-Nicotinamide ribose monophosphate,
|Related Categories||Biochemicals and Reagents, Cofactors, Enzymes, Inhibitors, and Substrates, Oxidation-Reduction|
|95-100% (spectrophotometric assay)|
Note: This is the common form of NMN. Do not confuse it with α-NMN.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N3501.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
Tailoring RNA modular units on a common scaffold: a modular ribozyme with a catalytic unit for β-nicotinamide mononucleotide-activated RNA ligation. Fujita Y, Furuta H, Ikawa Y. RNA 15, 877-888, (2009)
Evolutionary optimization of a modular ligase ribozyme: a small catalytic unit and a hairpin motif masking an element that could form an inactive structure. Fujita Y, Furuta H, Ikawa Y. Nucleic Acids Res. 38, 3328-3339, (2010)
Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides. Birrell JA and Hirst J Biochemistry 52(23), 4048-55, (2013)
Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase from porcine kidney in complex with nicotinate mononucleotide. Youn HS, Kim MK, Kang GB, et al. Acta Crystallogr. F, Struct. Biol. Cryst. Commun. 68(Pt 12), 1488-90, (2012)
Effects of long-acting somatostatin analogues on adrenal growth and phosphoribosyl pyrophosphate formation in experimental diabetes. Kunjara S, Greenbaum AL, Sochor M, et al. Int. J. Exp. Pathol. 93(1), 56-69, (2012)
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism. Garavaglia S, Bruzzone S, Cassani C, et al. Biochem. J. 441(1), 131-41, (2012)
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside. Bogan KL, Evans C, Belenky P, et al. J. Biol. Chem. 284(50), 34861-9, (2009)
Effect of nicotinamide mononucleotide on insulin secretion and gene expressions of PDX-1 and FoxO1 in RIN-m5f cells. Sheng F, Ren X, Dai X, et al. Zhong Nan Da Xue Xue Bao. Yi Xue Ban 36(10), 958-63, (2011)
Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues. Di Martino C and Pallotta ML Planta 234(4), 657-70, (2011)
Functional analysis of the nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) enzyme, involved in the late steps of coenzyme B12 biosynthesis in Salmonella enterica. Claas KR, Parrish JR, Maggio-Hall LA, et al. J. Bacteriol. 192(1), 145-54, (2010)
Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis. Galassi L, Di Stefano M, Brunetti L, et al Biochimie 94(2), 300-9, (2012)
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