EMAIL THIS PAGE TO A FRIEND

N3785 Sigma

Nabilone

solid, ≥98% (HPLC)

Synonym: LY-109514

  • CAS Number 51022-71-0

  • Empirical Formula (Hill Notation) C24H36O3

  • Molecular Weight 372.54

  •  MDL number MFCD00941490

Purchase

Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
assay   ≥98% (HPLC)
form   solid
drug control   USDEA Schedule II; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
color   white
solubility   DMSO: soluble ~18 mg/mL
  H2O: insoluble
shipped in   wet ice
storage temp.   2-8°C

Description

Biochem/physiol Actions

CB1 and CB2 cannabinoid receptor agonist.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability


Explore the New Analytical Standards Portal

DISCOVER Bioactive Small Molecules

Customers Also Viewed

(R,S)-AM1241

≥98% (HPLC), solid

AM251
A6226AM251

>98% (HPLC), solid

AM281
A0980AM281

≥98% (HPLC)

Cannabinol

analytical standard

CP-55940

>98% (HPLC), powder

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
WGK Germany 
3
RTECS 
HP8756000

Documents

Certificate of Analysis

Protocols & Articles

Peer-Reviewed Papers

References

Set your institution to view full text papers.

The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial. Ware MA, Fitzcharles MA, Joseph L, et al. Anesth. Analg. 110(2), 604-10, (2010)

Loading...


The abuse potential of the synthetic cannabinoid nabilone. Ware MA and St Arnaud-Trempe E Addiction 105(3), 494-503, (2010)

Loading...


An enriched-enrolment, randomized withdrawal, flexible-dose, double-blind, placebo-controlled, parallel assignment efficacy study of nabilone as adjuvant in the treatment of diabetic peripheral neuropathic pain. Toth C, Mawani S, Brady S, et al. Pain 153(10), 2073-82, (2012)

Loading...


[Marihuana and cannobinoids as medicaments]. Tkaczyk M, Florek E, and Piekoszewski W Prz. Lek. 69(10), 1095-7, (2012)

Loading...


[Cannabinoids in medicine]. Lenk R and Likar R Wien. Med. Wochenschr. 158(23-24), 668-73, (2008)

Loading...


[What sense in cannabinoid use as regulated by Italian DM 18/04/07? Pharmacological and legal considerations]. Molinelli A, Grossi S, Bonsignore A, et al. Minerva Med. 99(3), 335-40, (2008)

Loading...


Adjunctive nabilone in cancer pain and symptom management: a prospective observational study using propensity scoring. Maida V, Ennis M, Irani S, et al. J. Support. Oncol. 6(3), 119-24, (2008)

Loading...


Nabilone (Cesamet) for chemotherapy-induced nausea and vomiting. Med. Lett. Drugs Ther. 48(1249/1250), 103-4, (2006)

Loading...


Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Pertwee RG Br. J. Pharmacol. 156(3), 397-411, (2009)

Loading...


Separate and combined effects of the cannabinoid agonists nabilone and Δ⁹-THC in humans discriminating Δ⁹-THC. Lile JA, Kelly TH, and Hays LR Drug Alcohol Depend. 116(1-3), 86-92, (2011)

Loading...


Examining the roles of cannabinoids in pain and other therapeutic indications: a review. Turcotte D, Le Dorze JA, Esfahani F, et al. Expert Opin. Pharmacother. 11(1), 17-31, (2010)

Loading...


Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression. Moreira FA, Grieb M, and Lutz B Best Pract. Res. Clin. Endocrinol. Metab. 23(1), 133-44, (2009)

Loading...


Nabilone for the treatment of paraneoplastic night sweats: a report of four cases. Maida V J. Palliat. Med. 11(6), 929-34, (2008)

Loading...


A pilot study using nabilone for symptomatic treatment in Huntington's disease. Curtis A, Mitchell I, Patel S, et al. Mov. Disord 24(15), 2254-9, (2009)

Loading...


Nabilone. A preliminary review of its pharmacological properties and therapeutic use. Ward A and Holmes B Drugs 30(2), 127-44, (1985)

Loading...


Oral nabilone capsules in the treatment of chemotherapy-induced nausea and vomiting and pain. Davis MP Expert Opin. Investig. Drugs 17(1), 85-95, (2008)

Loading...


A randomized, double-blinded, crossover pilot study assessing the effect of nabilone on spasticity in persons with spinal cord injury. Pooyania S, Ethans K, Szturm T, et al. Arch. Phys. Med. Rehabil. 91(5), 703-7, (2010)

Loading...


An open-label comparison of nabilone and gabapentin as adjuvant therapy or monotherapy in the management of neuropathic pain in patients with peripheral neuropathy. Bestard JA and Toth CC Pain Pract. 11(4), 353-68, (2011)

Loading...


Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers. Bedi G, Cooper ZD, and Haney M Addict. Biol. 18(5), 872-81, (2013)

Loading...


Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting. Todaro B J. Natl. Compr. Canc. Netw. 10(4), 487-92, (2012)

Loading...


Analgesic and antihyperalgesic effects of nabilone on experimental heat pain. Redmond WJ, Goffaux P, Potvin S, et al. Curr. Med. Res. Opin. 24(4), 1017-24, (2008)

Loading...


Cloning and pharmacological characterization of the dog cannabinoid CB₂receptor. Ndong C, O'Donnell D, Ahmad S, et al. Eur. J. Pharmacol. 669(1-3), 24-31, (2011)

Loading...


Lack of effect of central nervous system-active doses of nabilone on capsaicin-induced pain and hyperalgesia. Kalliomäki J, Philipp A, Baxendale J, et al. Clin. Exp. Pharmacol. Physiol. 39(4), 336-42, (2012)

Loading...


Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial. Pini LA, Guerzoni S, Cainazzo MM, et al. J. Headache Pain 13(8), 677-84, (2012)

Loading...


Nabilone produces marked impairments to cognitive function and changes in subjective state in healthy volunteers. Wesnes KA, Annas P, Edgar CJ, et al. J. Psychopharmacol. 24(11), 1659-69, (2010)

Loading...


Substitution profile of the cannabinoid agonist nabilone in human subjects discriminating δ9-tetrahydrocannabinol. Lile JA, Kelly TH, and Hays LR Clin. Neuropharmacol. 33(5), 235-42, (2010)

Loading...


Nabilone in inflammatory pain: to be or not to be. Guindon J Clin. Exp. Pharmacol. Physiol. 39(4), 327-8, (2012)

Loading...


Cannabinoids in the treatment of symptoms in cancer and AIDS, 2nd edition #93. Wilner LS and Arnold RM J. Palliat. Med. 14(4), 509-10, (2011)

Loading...


Regulation of synthetic cannabinoids. Ashton CH and Moore PB Lancet 374(9701), 1595, (2009)

Loading...


Merck 14,6342

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?