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N3787 Sigma

Monoclonal Anti-Netrin-1 antibody produced in mouse

clone 158936, purified immunoglobulin, lyophilized powder

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neural Stem Cells, Antibodies for Neurobiology,
species reactivity   mouse
application(s)   direct ELISA: 0.5-1 μg/mL using rmNetrin-1
  western blot: 1-2 μg/mL using rmNetrin-1
clone   158936, monoclonal
antibody form   purified immunoglobulin
form   lyophilized powder
isotype   IgG2a
shipped in   wet ice
storage temp.   −20°C
Gene Information   mouse ... Ntn1(18208)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

purified, NS0-derived, recombinant mouse Netrin-1.

General description

Netrin-1 (NTN1) is a secreted protein.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Specificity

This antibody shows 100% cross-reactivity with rchNetrin-1 and no cross-reactivity with rhNetrin-2, rhNetrin-4, rmNetrin-4, or rmNetrin-G1a.

Legal Information

This product or the use of this product is covered by U.S. Patents owned by The Regents of the University of California. This product is for research use only and is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for such purposes, contact The Regents of the University of California. Patent numbers 5,565,331; 6,096,866; 6,017,714; 6,309,638; and 6,670,451.

Biochem/physiol Actions

Netrin-1 (NTN1) acts as a cardioprotectant. It can stimulate neovascularization of the retina in retinopathy. NTN1 has roles in angiogenesis and thymocyte adhesion.

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